MATRIX AND LAYER COMPOSITIONS FOR PROTECTION OF BIOACTIVES

摘要

The invention relates to matrix and layer compositions comprising a first polymer. The matrix and layer compositions are useful in the delivery of bioactives. In particular, the matrices and layers may have advantageous properties including mechanical properties and protection of bioactives and may also provide for pH-dependent release of a bioactive.

主权项

1. A composition comprising a layer formed over a core, the core comprising a bioactive agent, the layer comprising a first polymer comprising a repeat unit of Formula (I): wherein,
R2, R4, and R5 are independently chosen from hydrogen, hydrocarbyl, and substituted hydrocarbyl;R6 is chosen from hydrogen, hydrocarbyl, and substituted hydrocarbyl;R7 is optionally present, when present it is chosen from hydrogen, hydrocarbyl, and substituted hydrocarbyl;Z is chosen from sulfur, sulfone, sulfoxide, and selenium;n is an integer ≧1; andm is an integer >1.