Methods of Drying Sheets of Tissue

摘要

Embodiments of the technology may involve a method of processing the human donor tissue for administration to a recipient. This method may include the step of contacting the human donor tissue with a backing layer, where the human donor tissue and the backing layer contain a saline solution. This saline solution may include a solvent and a disassociated salt. The method may further include evaporating a portion of the solvent from a surface of the backing layer. The evaporation of the solvent may move a portion of the disassociated salt from the donor tissue to the backing layer. This process may then result in a tissue that is mostly dry and free of salt crystals.

主权项

1. A method of processing an amniotic tissue for administration to a recipient patient, comprising the steps of
treating the amniotic tissue with a glutaraldehyde solution; rinsing the amniotic tissue with a first saline solution; contacting the amniotic tissue with a first backing layer and a second backing layer, wherein the amniotic tissue contains a second saline solution comprising a solvent and a dissociated salt; restraining the amniotic tissue and the first and second backing layers between a first plate and a second plate; pressing together the amniotic tissue and the first and second backing layers; and evaporating a portion of the solvent from a surface of the first or the second backing layer, so as to move a portion of the dissociated salt from the amniotic tissue into the first backing layer or the second backing layer, wherein evaporating comprises maintaining a temperature around the amniotic tissue at below about 40° C.