发明名称 |
ANALYZING IMMUNE SIGNALING NETWORKS FOR IDENTIFICATION OF THERAPEUTIC TARGETS IN COMPLEX CHRONIC MEDICAL DISORDERS |
摘要 |
A general method of analyzing immune signaling networks for identification of potential therapeutic targets in complex, chronic medical disorders is described. The disclosure provides the CD3-/CD56+ natural killer (NK) cell population as a potential therapeutic target in the clinically-overlapping disorders Gulf War Illness (GWI) and Myalg Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The disclosure also provides a method for improving or restoring Natural Killer (NK) cell function by stimulating the NK cells with interleukin- 15 (IL-15). |
申请公布号 |
WO2015054701(A3) |
申请公布日期 |
2015.06.11 |
申请号 |
WO2014US60535 |
申请日期 |
2014.10.14 |
申请人 |
NOVA SOUTHEASTERN UNIVERSITY |
发明人 |
FLETCHER, MARY, ANNE;BRODERICK, GORDON;KLIMAS, NANCY |
分类号 |
C12Q1/02;A61K38/00;G01N33/00;G01N33/48;G01N33/567;G06F7/60 |
主分类号 |
C12Q1/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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