发明名称 |
MICROORGANISMS AND METHODS FOR THE PRODUCTION OF KETONES |
摘要 |
The invention provides a recombinant, acetogenic, carboxydotrophic bacterium that lacks secondary alcohol dehydrogenase or comprises an inactivated secondary alcohol dehydrogenase. The inactivated secondary alcohol dehydrogenase may be encoded by a secondary alcohol dehydrogenase gene comprising an inactivating mutation that reduces the ability of the bacterium to convert acetone to isopropanol and to convert methyl ethyl ketone to 2-butanol. Since a bacterium that lacks secondary alcohol dehydrogenase or comprises an inactivated secondary alcohol dehydrogenase accumulates carbonyl-containing compounds, the invention also provides a method of producing carbonyl-containing compounds, such as acetone and methyl ethyl ketone. |
申请公布号 |
CA2931627(A1) |
申请公布日期 |
2015.06.11 |
申请号 |
CA20142931627 |
申请日期 |
2014.12.03 |
申请人 |
LANZATECH NEW ZEALAND LIMITED |
发明人 |
MUELLER, ALEXANDER PAUL;KOEPKE, MICHAEL;AL-SINAWI, BAKIR;JENSEN, RASMUS OVERGAARD;HILL, RYAN EDWARD |
分类号 |
C12N1/21;C12N9/04;C12P7/62 |
主分类号 |
C12N1/21 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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