发明名称 |
Papillomavirus Pseudoviruses for Detection and Therapy of Tumors |
摘要 |
Disclosed herein are methods of detecting tumors, monitoring cancer therapy, and selectively inhibiting the proliferation and/or killing of cancer cells utilizing a papilloma pseudovirus or a papilloma virus-like particle (VLP) |
申请公布号 |
US2015157738(A1) |
申请公布日期 |
2015.06.11 |
申请号 |
US201414558301 |
申请日期 |
2014.12.02 |
申请人 |
The USA, as represented by the Secretary, Dept. of Health and Human Services |
发明人 |
Roberts Jeffrey;Lowy Douglas R.;Schiller John T. |
分类号 |
A61K49/00;A61K31/7088;A61K31/522;A61K51/12;A61K35/76 |
主分类号 |
A61K49/00 |
代理机构 |
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代理人 |
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主权项 |
1. A method of detecting the presence of cancer cells bound to a papilloma pseudovirus or a papilloma VLP comprising:
identifying a subject having or suspected of having cancer cells; administering to said subject a detectable amount of a papilloma pseudovirus or a papilloma VLP that comprises a detectable label; and detecting the presence of cancer cells bound to said papilloma pseudovirus or said papilloma VLP that comprises a detectable label. |
地址 |
Bethesda MD US |