发明名称 |
INHIBITORS OF BRUTON'S TYROSINE KINASE |
摘要 |
Disclosed herein are reversible and irreversible inhibitors of Bruton's tyrosine kinase (Btk). Also disclosed are pharmaceutical compositions that include the compounds. Methods of using the Btk inhibitors are described, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions. |
申请公布号 |
CA2932609(A1) |
申请公布日期 |
2015.06.11 |
申请号 |
CA20142932609 |
申请日期 |
2014.12.03 |
申请人 |
PHARMACYCLICS LLC |
发明人 |
JIA, ZHAOZHONG J.;THOMAS, WILLIAM D.;CHEN, WEI |
分类号 |
C07D403/12;A61K31/497;A61K31/53;A61P19/00;A61P35/00;A61P37/00;C07D401/04;C07D401/12;C07D401/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D471/04 |
主分类号 |
C07D403/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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