发明名称 |
Bivalent Ligands for the Treatment of Neurological Disorders |
摘要 |
Bivalent ligands that contain two pharmacophores linked through a spacer, one of which interacts with the μ-opioid receptor (MOR) and the other of which interacts with the co-receptor CC chemokine receptor 5 (CCR5), are used for the treatment of neurological disorders such as those associated with AIDS. |
申请公布号 |
US2015157730(A1) |
申请公布日期 |
2015.06.11 |
申请号 |
US201414568859 |
申请日期 |
2014.12.12 |
申请人 |
Virginia Commonwealth University |
发明人 |
Zhang Yan;Hauser Kurt F.;Selley Dana E. |
分类号 |
A61K47/48;A61K31/485 |
主分类号 |
A61K47/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
Richmond VA US |