| 摘要 |
Provided is a multi-arm polyethylene glycol-nitrine derivative of general formula I, wherein R is a central molecule; the derivative is selected from a polyhydroxy structure, a polyamino structure or a polycarboxyl structure; n is the number of branches or arms, n≥3; PEG is the same or different -(CH2CH2O)m-, the average value of m being an integer from 3 to 250; X is a linking group of a nitrine end group; k is the number of the branches having the nitrine end group; F is selected from the group consisting of amino, carboxyl, sulfhydryl, ester group, Malaya amide group and acrylic group; and Y is a linking group of an end group F. |
