发明名称 FORMS OF THE EGFR INHIBITOR
摘要 The present disclosure generally relates to polymorphic form(s) of (R,E)-N-(7-chloro-1-(1-(4-(dimethylamino)but-2-enoyl)azepan-3-yl)-1H-benzo[d]imidazol-2 -yl)-2-methylisonicotinamide (Compound EGFRi). The present disclosure also generally relates to a pharmaceutical composition comprising the form(s), as well of methods of using the form(s) in the treatment of cancer indications, and methods for obtaining such forms.
申请公布号 WO2015083059(A1) 申请公布日期 2015.06.11
申请号 WO2014IB66475 申请日期 2014.12.01
申请人 NOVARTIS AG;SETHURAMAN, VIJAY;WAYKOLE, LILADHAR;LI, RUNYAN;MAO, LIANG;PAN, WENXIAN;WANG, XIAOYANG;ZHANG, YUBO 发明人 SETHURAMAN, VIJAY;WAYKOLE, LILADHAR;LI, RUNYAN;MAO, LIANG;PAN, WENXIAN;WANG, XIAOYANG;ZHANG, YUBO
分类号 C07D401/14;A61K31/4439 主分类号 C07D401/14
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