发明名称 DIAGNOSTIC TECHNIQUE FOR DISTURBED ENDOMETRIAL RECEPTIVITY IN PATIENTS SUFFERING UTERINE MYOMA AND INFERTILITY
摘要 FIELD: medicine.SUBSTANCE: technique consists in measuring a pinopod count in the germinal epithelium, an expression level of progesterone and oestrogen alpha receptors in the endometrial stroma, calculating their ratio, and determining an expression level of implantation LIF factor on the 21-24day of the menstrual cycle ('implantation window'). If the pinopod count is less than 35%, the expression ratio of progesterone and oestrogen alpha receptors in the endometrial stroma less than 3.5, as well as the LIF expression level of less than 2 points, disturbed fertility associated with uterine myoma is diagnosed.EFFECT: technique enables applying the differentiated approach to managing the patients planning pregnancy, suffering uterine myoma undeforming the uterine cavity, as well as with myomatous nodule up to 5,0 cm in diameter.2 ex, 4 dwg
申请公布号 RU2553340(C1) 申请公布日期 2015.06.10
申请号 RU20140115770 申请日期 2014.04.21
申请人 FEDERAL'NOE GOSUDARSTVENNOE BJUDZHETNOE UCHREZHDENIE "NAUCHNYJ TSENTR AKUSHERSTVA, GINEKOLOGII I PERINATOLOGII IMENI AKADEMIKA V.I. KULAKOVA" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII 发明人 ASKOL'SKAJA SVETLANA IVANOVNA;KOGAN EVGENIJA ALTAROVNA;CHUPRYNIN VLADIMIR DMITRIEVICH;BURYKINA POLINA NIKOLAEVNA;DEMURA TAT'JANA ALEKSANDROVNA;POPOV JURIJ VJACHESLAVOVICH
分类号 G01N33/48 主分类号 G01N33/48
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