发明名称 METHOD OF DIAGNOSING HUNTINGTON'S DISEASE
摘要 FIELD: medicine.SUBSTANCE: examination of the area of the optic nerve disc by a method of optic coherent tomography is carried out. The thickness of a layer of peripapillary nervous fibres from 4 to 8 sector of a conventional clock face is determined. If the thickness of the layer of peripapillary nervous fibres in as minimum one of the sectors is lower than 34.81-35.84 mcm - in 4 sector, lower than 48.92-49.52 mcm - in 5 sector, lower than 67.76-68.56 mcm - in 6 sector, lower than 66.52-67.32 mcm - in 7 sector, lower than 32.98-33.76 mcm - in 8 sector, Huntington's disease is diagnosed. If the thickness of the layer of peripapillary nervous fibres in all segments in 4 sector is 34.81-35.84 mcm and higher, in 5 sector is 48.92-49.52 mcm and higher, in 6 sector is 67.76-68.56 mcm and higher, in 7 sector is 66.52-67.32 mcm and higher, in 8 sector is 32.98-33.76 mcm and higher, the absence of Huntington's disease in the patient is diagnosed.EFFECT: method provides a possibility of disease express-diagnostics at a pre-clinical stage with high accuracy and specificity, provides a possibility of performing screening diagnostics of a large population of people aimed at early disease detection.2 dwg, 3 ex
申请公布号 RU2552913(C1) 申请公布日期 2015.06.10
申请号 RU20140111407 申请日期 2014.03.25
申请人 GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "NIZHEGORODSKAJA GOSUDARSTVENNAJA MEDITSINSKAJA AKADEMIJA" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII (GBOU VPO NIZHGMA MINZDRAVA ROSSII) 发明人 KOPISHINSKAJA SVETLANA VASIL'EVNA;ANTONOVA VIKTORIJA ANTONOVNA;GUSTOV ALEKSANDR VASIL'EVICH;SVETOZARSKIJ SERGEJ NIKOLAEVICH
分类号 A61B8/14 主分类号 A61B8/14
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