发明名称 NEUTRALISING ANTI-INFLUENZA A VIRUS ANTIBODIES AND USING THEM
摘要 FIELD: medicine, pharmaceutics.SUBSTANCE: presented invention refers to immunology. There are presented versions of antibodies neutralising a subtype group 1 and subtype group 2 influenza A virus infection. The antibody is characterised by: either a set of 3 CDR of a light and 3 CDR of a heavy chain, or the presence of variable regions of the light and heavy chains. There are disclosed: a nucleic acid molecule coding the antibody; a cell expressing the antibody; as well as a method for the attenuation of the influenza A virus infection or reducing a risk thereof with the use of the antibody in a therapeutically or preventatively effective amount.EFFECT: using the invention provides the antibodies neutralising the influenza A virus, which can find application in medicine in treating subtypes H1, H2, H3, H5, H7, H9 influenza.18 cl, 6 tbl, 2 ex
申请公布号 RU2553325(C2) 申请公布日期 2015.06.10
申请号 RU20110105062 申请日期 2009.07.27
申请人 INSTITUT FO RESECH IN BIOMEDITSIN 发明人 LANZAVESHIJA, ANTONIO
分类号 C07K16/10;A61K39/395;A61P31/16;C12N5/10;C12N15/13 主分类号 C07K16/10
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