| 发明名称 | Polypeptides isolated from <i>brevibacterium aurantiacum </i>and their use for the treatment of cancer | ||
| 摘要 | The present invention relates to methods and pharmaceutical compositions for treating cancer. More specifically, the invention relates to a polypeptide isolated from Brevibacterium aurantiacum that shows methionine gamma-lyase and homocysteinase activities. The present invention also relates to the use of such a polypeptide for the treatment of cancer. | ||
| 申请公布号 | US9051562(B2) | 申请公布日期 | 2015.06.09 |
| 申请号 | US201214126253 | 申请日期 | 2012.06.15 |
| 申请人 | Institut National de la Santé et de la Recherche Médicale (INSERM);INRA (Institut National de la Recherche Agronomique);UNIVERSITE PARIS SUD-PARIS XI | 发明人 | Machover David;Bonnarme Pascal |
| 分类号 | C07K14/345;A61K38/00;C12N9/88;C12N9/14;C07K14/435 | 主分类号 | C07K14/345 |
| 代理机构 | Whitham Curtis Christofferson & Cook, PC | 代理人 | Whitham Curtis Christofferson & Cook, PC |
| 主权项 | 1. A vector comprising a nucleic acid encoding a polypeptide comprising an amino acid sequence as set forth by SEQ ID NO: 1 or a functionally-conservative variant thereof. | ||
| 地址 | Paris FR | ||