Methods for triazole synthesis

摘要

Disclosed are methods of synthesizing triazoles that avoids the use of concentrated acids in favor of carbonic acid generated from CO2 that can be practiced at ambient and/or elevated temperature and/or atmospheric and/or elevated pressures. The disclosed methods also provide a way of synthesizing triazole products that are sufficiently pure and/or of sufficient concentration whereby the reaction product(s) may not require purification or other treatment before being used in, for example, formulating water treatment compositions that will tend to suppress corrosion or as an intermediate product in a more complex synthesis.

主权项

1. A method for synthesizing a 1,2,3-triazole compound in an aqueous solution comprising:
forming an aqueous solution of a diamine and a nitrite salt; introducing carbon dioxide into the aqueous solution to form carbonic acid; reacting a portion of the carbonic acid with the nitrite salt to produce nitrous acid and a bicarbonate; and reacting the diamine with a portion of the nitrous acid for a reaction period at a reaction pressure and a reaction temperature sufficient to produce the 1,2,3-triazole compound.