Joint repair using mesenchymal stem cells

摘要

A method of repairing and/or stabilizing a joint by administering mesenchymal stem cells to the joint. Such a method provides for the regeneration of cartilaginous tissue in the joint, including meniscal tissue.

主权项

1. A method of repairing damaged meniscal tissue in a joint of a human, comprising:
administering directly to said joint via intra-articular injection a liquid suspension comprising isolated allogeneic mesenchymal stem cells and an acceptable pharmaceutical carrier in an amount effective to repair damaged meniscal tissue in a joint of the animal, wherein the mesenchymal stem cells differentiate into and/or stimulate production of meniscal tissue, wherein the suspension is administered in the absence of a scaffold and wherein the pharmaceutical carrier is saline.