Method and apparatus for the detection of impaired dark adaptation

摘要

The present method describes a new method for the measurement of dark adaptation. The dark adaptation status of subjects may then be used to identify those subjects who are at risk of developing and/or who are currently suffering from a variety of disease states having their clinical manifestations in impaired dark adaptation. The disease states include, but are not limited to, age related macular degeneration, vitamin A deficiency, Sorsby's Fundus Dystrophy, late autosomal dominant retinal degeneration, retinal impairment related to diabetes and diabetic retinopathy. An apparatus for administering the test method described is also provided.

主权项

1. A method for psychophysical measurement of dark adaptation in a subject, said method comprising the steps of:
a. providing said subject; b. bleaching a test eye of said subject; c. presenting a target stimulus to said test eye of said subject; and d. determining a response of said subject to said target stimulus by obtaining at least one threshold measurement or a partial threshold curve, wherein said at least one threshold measurement or said partial threshold curve is predominately obtained in the second component of the rod mediated recovery.