| 发明名称 | Surgical applications for BMP binding protein | ||
| 摘要 | The present invention relates to the clinical application of BBP, alone or in combination with other growth factors, for use in bone healing applications, such as spinal surgery. Additional applications include use in orthopedic implantable prostheses and implantation into other surgical sites (e.g., surgical reconstruction, regional osteopenia, etc.) where bone is desired. | ||
| 申请公布号 | US9050300(B2) | 申请公布日期 | 2015.06.09 |
| 申请号 | US201313857711 | 申请日期 | 2013.04.05 |
| 申请人 | The Regents of The University of California;The United States of America Represented by The Department of Veterans Affairs | 发明人 | Murray Samuel S.;Brochmann-Murray Elsa J.;Behnam Keyvan;Wang Jeffrey C. |
| 分类号 | A61K38/18;A61K38/10;A61K35/32;C07K4/12;C07K14/495;C07K14/51 | 主分类号 | A61K38/18 |
| 代理机构 | McDermott Will & Emery LLP | 代理人 | McDermott Will & Emery LLP |
| 主权项 | 1. A method of increasing the rate of bone formation in vertebrate tissue, comprising applying to a tissue a peptide having the sequence of SEQ ID NO: 11, or a fragment thereof, and a dose of least one bone growth factor, wherein the combination results in a faster rate of bone formation than treatment with the same dose of the at least one bone growth factor alone. | ||
| 地址 | Oakland CA US | ||