Fast pinhole changer for confocal microscopy or spatial filter

摘要

A pinhole changing device for a confocal microscope is detailed herein. Several pinholes of different sizes are contained on a single disk. A precision XY stage is used to switch between the several pinholes. The same device could be used as a spatial filter for a multi-photon microscope. One can also add beam expansion control and spherical aberration correction to the same device with no additional loss.

主权项

1. A confocal microscope pinhole changing device comprising:
a light-blocking part located between two lenses with at least two pinhole apertures of at least two different sizes to block out-of-focus light; an optical system adapted to focus light through at least one of the pinholes; and a device adapted to move the light-blocking part to select which of the at least one pinhole is in focus of optics.