发明名称 |
Dry powder formulations of particles that contain two or more active ingredients for treating obstructive or inflammatory airways diseases |
摘要 |
Dry powder formulations for inhalation comprising spray-dried particles and their use in the treatment of an obstructive or inflammatory airways disease. Each particle has a core of a first active ingredient in substantially crystalline form that is coated with a layer of a second active ingredient in substantially amorphous form that is dispersed in a pharmaceutically acceptable hydrophobic excipient. A process for preparing such formulations is also described. |
申请公布号 |
US9050267(B2) |
申请公布日期 |
2015.06.09 |
申请号 |
US201213982630 |
申请日期 |
2012.02.03 |
申请人 |
Novartis AG |
发明人 |
Weers Jeffry G.;Rao Nagaraja;Huang Daniel;Miller Danforth;Tarara Thomas E. |
分类号 |
A61K9/14;A61K9/50;A61K9/00;A61K45/06;A61K31/40;A61K31/4704;A61K31/56;A61K31/58;A61M15/00;A61K9/16 |
主分类号 |
A61K9/14 |
代理机构 |
|
代理人 |
Woods Daniel |
主权项 |
1. A dry powder formulation for inhalation comprising spray-dried particles that comprise a core of a first active ingredient in substantially crystalline form that is coated with a layer of a second active ingredient in substantially amorphous form that is dispersed in a pharmaceutically acceptable hydrophobic excipient. |
地址 |
Basel CH |