| 摘要 |
The present invention describes compounds of formula (I);
Wherein:
R1 is selected from C1-C6 alkyl, CF3, Phenyl & 2-thienylR2 is selected from C1-C6 alkyl, phenyl & CF3 R3 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkylR4 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkylR5 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkylR6 is selected from H, —(CH2)nC(O)OR7 & C(O)C6H4—R7 R7 is selected from C1-C6 alkyl, phenyl optionally substituted by 1-3 substituents selected from CF3, NO2 and halo.n is 0-6;These compounds have been identified as novel anticancer agents. |
| 主权项 |
1. A compound of formula (I) Wherein: R1 is selected from C1-C6 alkyl, CF3, Phenyl & 2-thienyl R2 is selected from C1-C6 alkyl, phenyl & CF3 R3 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkyl R4 is selected from H, C1-C6 alkyl, halo, NO2, NH2, haloalkyl R5 is selected from, C1-C6 alkyl, F, NO2, NH2, haloalkyl R6 is selected from H, —(CH2)nC(O)OR7 & C(O)C6H4—R7 R7 is selected from C1-C6 alkyl, phenyl optionally substituted by 1-3 substituents selected from CF3, NO2 and halo n is 0-6 wherein, when R1 & R2 are both CH3, R5 is not NO2, CH3, C2H5, Cl, Br, I or H and R4 is not NO2, CH3, C2H5, Cl, Br or H and when R1 & R2 are both phenyl, R5 is not NO2, Cl, Br, I or CH3 and R4 is not NO2. |
