发明名称 Compositions and methods for delivery of frozen particle adhesives
摘要 Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.
申请公布号 US9050251(B2) 申请公布日期 2015.06.09
申请号 US200912383263 申请日期 2009.03.20
申请人 The Invention Science Fund I, LLC 发明人 Boyden Edward S.;Cook Daniel B.;Hyde Roderick A.;Leuthardt Eric C.;Myhrvold Nathan P.;Sweeney Elizabeth A.;Wood, Jr. Lowell L.
分类号 A61K9/00;A61K9/16;A61K9/08;A61K31/00;A61K51/12;A61K9/19;A61K31/10;A61K31/337;A61K31/70;A61K31/7088;A61K33/00;A61K41/00;A61K45/06;A61K49/18;A61K39/00 主分类号 A61K9/00
代理机构 代理人
主权项 1. A frozen particle composition, comprising: one or more frozen saline solution particles including at least one adhesive agent substantially in the form of a vesicle and including an acrylic polymer; and wherein the frozen particle composition is externally coated with at least one anesthetic, analgesic, or antimicrobial agent, wherein the analgesic or anesthetic includes at least one of an aminoamid or aminoester local anesthetic, ibuprofen, morphine, codeine, lidocaine/lignocaine, ropivacaine, mepivacaine, benzocaine, chloroprocaine, cyclomethycaine, dimethocaine/larocaine, propoxycaine, procaine/novocaine, proparacaine, tetracaine/amethocaine, articaine, bupivacaine, carticaine, cinchocaine/dibucaine, etidocaine, levobupivacaine, piperocaine, prilocaine, trimecaine, saxitoxin, tetrodotoxin, acetaminophen, a non-steroidal anti-inflammatory drug, salicylate, narcotic, or tramadol; and wherein the antimicrobial agent includes at least one of an anti-fungal agent, antibiotic agent, anti-bacterial agent, anti-parasitic agent, or anti-worm agent.
地址 Bellevue WA US