摘要 |
The invention provides murine, chimeric, and humanized antibodies that specifically bind to CD33. The antibodies are useful for treatment and diagnoses of various cancers as well as detecting CD33. The monoclonal antibodies contain complementarily determining regions (CDRs) of SEQ ID NOs: 19, 20, and 21 in the heavy chain variable region and CDRs of SEQ ID NOs: 22, 23, and 24 in the light chain variable region. |