SILICON-BASED CROSS COUPLING AGENTS AND METHODS OF THEIR USE

摘要

Compositions and methods using silicon-based cross-coupling agents in the formation of carbon-carbon and carbon-nitrogen bonds are described.

主权项

1. A compound of formula I: wherein Y is CH or N; R1 and R2 are independently C1-10 straight or branched-chain alkyl optionally substituted with one or more halogen, nitro, C1-6alkoxy, or aryl; R3 is H;
aryl optionally substituted with one or more nitro, diC1-6alkylamino, C1-6alkoxy, or C1-6alkyl;heteroaryl optionally substituted with one or more nitro, diC1-6alkylamino, C1-6alkoxy, or C1-6alkyl;C1-10 straight or branched-chain alkyl optionally substituted with one or more halogen, nitro, C1-6alkoxy, or aryl;a polymer; ora resin support; R3a is H or C1-6alkyl optionally substituted with one or more halogen; and at least one R4, wherein each R4 is independently hydrogen, halogen, nitro, C1-6alkoxy, C1-6alkyl, aryl, or a resin support.