发明名称 |
DOSAGE THAT IS SAFEGUARDED FROM ABUSE |
摘要 |
The invention relates to a dosage form that is thermoshaped without being extruded and that is safeguarded from abuse, comprising at least one synthetic or natural polymer having a breaking strength of at least 500 N in addition to one or more active substances that could be subject to abuse and optionally physiologically acceptable adjuvants. The invention also relates to a corresponding method for producing said dosage form. |
申请公布号 |
US2015150978(A1) |
申请公布日期 |
2015.06.04 |
申请号 |
US201514618030 |
申请日期 |
2015.02.10 |
申请人 |
GRÜNENTHAL GMBH |
发明人 |
Arkenau-Maric Elisabeth;Bartholomäus Johannes;Kugelmann Heinrich |
分类号 |
A61K47/10;A61K9/20;A61K31/135 |
主分类号 |
A61K47/10 |
代理机构 |
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代理人 |
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主权项 |
1. An abuse-proofed dosage form thermoformed by extrusion without discoloration, wherein, in addition to one or more active ingredients with abuse potential (A) optionally together with physiologically acceptable auxiliary substances (B), it contains at least one synthetic or natural polymer (C) and optionally at least one wax (D), wherein component (C) and the optionally present component (D) exhibit a breaking strength of at least 500 N. |
地址 |
Aachen DE |