Label-Free Cellular Manipulation and Sorting Via Biocompatible Ferrofluids

摘要

A device for separating a sample of cells suspended in a bio-compatible ferrofluid is described, The device includes a microfluidic channel having a sample inlet, at least one outlet and a length between the same inlet and the at least one outlet, wherein a sample can be added to the sample inlet and flow along the microfluidic channel length to the at least one outlet. The device includes a plurality of electrodes and a power source for applying a current to the plurality of electrodes to create a magnetic field pattern along the microfluidic channel length. The present invention also includes a method of using said device for separating at least one cell type.

主权项

1. A method for separating at least one target particle from a sample, the method comprising:
suspending two or more particles in a biocompatible ferrofluid to form a sample; passing the sample through a microfluidic channel; and applying a magnetic field pattern along the microfluidic channel, the magnetic field pattern configured to sort the at least one target particle of the two or more particles into at least one outlet based on one or more characteristics of the at least one target particle.