PHARMACEUTICAL COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF DEGENERATIVE RETINAL DISEASES

摘要

The invention relates to a composition comprising mesenchymal stem cells (MSCs), preferably originating from adipose tissue (AD-MSCs), combined with vasoactive intestinal peptide (VIP) and nicotinamide (NIC) and, more preferably, also combined with retinoic acid (ATRA) and with supernatant of a cell culture of retinal pigment epithelium (RPE). The invention also relates to the use of this composition for the treatment and/or prevention of retinal damage, preferably degenerative diseases of the retina, for example, but not limited to, degenerative diseases of the RPE, of the photoreceptors and of the neuroretina.