| 发明名称 |
MATRIX METALLOPROTEINASE CLEAVABLE PROTEIN POLYMERS FOR CANCER GENE THERAPY |
| 摘要 |
A delivery system that includes a recombinantly synthesized protein polymer with protease cleavage sites such as matrix metalloproteinase responsive sequences engineered within the protein polymer. The system may be used to treat cancer, wounds, or pathological conditions in other tissues that express excess protease relative to healthy tissue. |
| 申请公布号 |
US2015152165(A1) |
申请公布日期 |
2015.06.04 |
| 申请号 |
US201314403979 |
申请日期 |
2013.05.30 |
| 申请人 |
The University of Utah Research Foundation |
发明人 |
Ghandehari Hamidreza;Cappello Joseph;Frandsen Jordan;Gustafson Joshua;Greish Khaled;Price Robert Andrew |
| 分类号 |
C07K14/78;A61K31/522;C12N7/00;A61K38/39;A61K38/45 |
主分类号 |
C07K14/78 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A protein polymer comprising one or more enzymatic cleavage sites wherein the protein polymer is produced using recombinant methods. |
| 地址 |
Salt Lake City UT US |
