NEW CARBAMATE GLYCOLIPID AND USE THEREOF

摘要

The invention provides a compound effective as an antitumor active agent or vaccine adjuvant and an intermediate useful for the synthesis of the compound, as well as production methods thereof, and a medicament containing the novel compound. The compound is a carbamate glycolipid represented by the formula (I);;wherein each symbol is as defined herein. The invention also provides a dendritic cell pulsed with the glycolipid.

主权项

1. A compound represented by the formula (I) wherein X is an alkylene group or —NH—; R1 and R2 are the same or different and each is a hydrogen atom, an alkyl group, a hydroxyl group, an alkoxy group, or an aryl group optionally having substituent(s), R1 and R2 optionally form, together with the adjacent nitrogen atom, a 5- or 6-membered ring; R3 is a hydrocarbon group having 1-20 carbon atoms; and R4 is a hydrocarbon group having 1-30 carbon atoms, or a salt thereof.