发明名称 BENZOXAZINON DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING UROTENSIN-II RECEPTOR HYPERACTIVITY-RELATED DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT
摘要 The present invention relates to a benzoxazinon derivative or a pharmaceutically acceptable salt thereof, a preparation method therefor, and a pharmaceutical composition for preventing or treating urotensin-II receptor hyperactivity-related diseases containing the same as an active ingredient. The benzoxazinon derivative according to the present invention acts as an antagonist of a urotensin-II receptor, and thus can be usefully used for preventing, ameliorating or treating urotensin-II receptor hyperactivity-related diseases such as congestive heart failure, heart ischemia, myocardial infarction, cardiomegalia, myofibrosis cordis, coronary artery disease, arteriosclerosis, hypertension, asthma, renal failure, diabetes, vascular inflammation, degenerative neuronal disease, stroke, pain, depression, mental illness, and cancer.
申请公布号 WO2015080388(A1) 申请公布日期 2015.06.04
申请号 WO2014KR10298 申请日期 2014.10.30
申请人 KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY 发明人 LEE, BYUNG HO;YI, KYU YANG;OH, KWANG-SEOK;LIM, CHAE JO;LEE, JEONG HYUN;KIM, NACK JEONG;SUH, JEE HEE;SEO, HO WON
分类号 C07D413/14;A61K31/538 主分类号 C07D413/14
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