| 发明名称 |
AN IL-15 AND IL-15R/alpha SUSHI DOMAIN BASED IMMUNOCYTOKINES |
| 摘要 |
The immunocytokine includes (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to the conjugate, wherein the conjugate includes (i) a polypeptide including the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide including the amino acid sequence. |
| 申请公布号 |
US2015152188(A1) |
申请公布日期 |
2015.06.04 |
| 申请号 |
US201214129188 |
申请日期 |
2012.06.22 |
| 申请人 |
CYTUNE ;INSERM |
发明人 |
Morisseau Sebastien Daniel;Teppaz Géraldine;Jacques Yannick Laurent Joseph;Robert Bruno Gilbert Marc;De Martynoff Guy Luc Michel;Bechard David |
| 分类号 |
C07K16/32;C07K16/30;C07K16/28;C07K14/715 |
主分类号 |
C07K16/32 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An immunocytokine comprising:
a) a conjugate, and b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises: (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and (ii) a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15Rα or derivatives thereof. |
| 地址 |
Nantes FR |
