| 摘要 |
<p>The present invention relates to topical ophthalmic compositions for treating or preventing epithelial lesions or ophthalmic disorders, including dry eye or keratoconjunctivitis sicca. The present invention provides a method of treating dry eye by topically administering to the eye a human conjunctiva-derived mucin containing composition, which derived mucin is similar to those of the transmembrane mucin expressed on the ocular surface epithelium, and to the gel-forming mucins secreted by the goblet cells, in addition, said composition may comprise a fraction enriched with exosomes. The compositions of this invention protect the ocular surface from dryness and absorb shear forces of the blink.</p> |
