| 发明名称 |
HERPESVIRUS COMPOSITIONS AND RELATED METHODS |
| 摘要 |
The present disclosure relates to liquid and dried compositions comprising a live, attenuated or genetically modified herpesvirus and methods of preparing such compositions, in one aspect, the composition comprises at least two or more pharmaceutically acceptable excepients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. The compositions retain a sufficiently high infectious titre following storage or large-scale manufacturing steps, such as lyophilization. |
| 申请公布号 |
US2015150964(A1) |
申请公布日期 |
2015.06.04 |
| 申请号 |
US201314402678 |
申请日期 |
2013.05.21 |
| 申请人 |
SANOFI PASTEUR LIMITED ;SANOFI PASTEUR BIOLOGICS, LLC |
发明人 |
Anderson Stephen;Delagrave Simon;Hamberger John;Li Qinglian;Mundle Sophia;Rahman Nausheen |
| 分类号 |
A61K39/245;C12N7/00 |
主分类号 |
A61K39/245 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising a live, attenuated or genetically modified herpesvirus, and at least two or more pharmaceutically acceptable excipients, at least one of which is histidine and at least one of which is a sugar or sugar alcohol. |
| 地址 |
TORONTO CA |
