| 主权项 |
1. A method of treating a disease, symptom, or condition associated with a T-type calcium ion channel, comprising:
a) administering to a patient in need thereof a therapeutically effective amount of a compound of formula (Ib), or a salt or ester thereof,wherein,
A1 is O or S; R4 is hydrogen, C1-6 alkyl, substituted C1-6 alkyl, C1-6 heteroalkyl, substituted C1-6 heteroalkyl, hydroxyl, C1-6 alkoxy, amino, or C1-6 alkamino; L is —CHOH—; each R5 and R6 is independently halo, alkyl, substituted alkyl, heteroalkyl, substituted heteroalkyl, hydroxyl, alkoxy, amino, alkamino, cyano, or nitro; m is an integer of 0, 1, or 2; and n is an integer of 0, 1, or 2. |
