| 发明名称 |
COMPOUNDS AND COMPOSITIONS FOR TREATMENT OF CANCER |
| 摘要 |
Compounds and compositions for treating, preventing or managing cancer are disclosed. The compositions provided herein comprise SNS-595 and N-desmethyl-SNS-595. Also provided are pharmaceutical compositions comprising the compounds and methods of treatment using the compounds and compositions. |
| 申请公布号 |
US2015150858(A1) |
申请公布日期 |
2015.06.04 |
| 申请号 |
US201414320414 |
申请日期 |
2014.06.30 |
| 申请人 |
SUNESIS PHARMACEUTICALS, INC. |
发明人 |
ADELMAN Daniel C.;EVANCHIK Marc J.;SUDHAKAR Anantha;JACOBS Jeffrey William;SILVERMAN Jeffrey A. |
| 分类号 |
A61K31/4375 |
主分类号 |
A61K31/4375 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising about 97% to about 99.99% by weight of (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid and from about 0.01% up to about 3% by weight of an N-desmethyl (+)-1,4-dihydro-7-[(3S,4S)-3-methoxy-4-(methylamino)-1-pyrrolidinyl]-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid, wherein each of the percentage is based upon total weight of the two components. |
| 地址 |
South San Francisco CA US |
