The present invention relates to HMGB1 variants that maintain HMGB1 wild type chemoattractant function while displaying abolished cytokine and/or chemokine stimulating properties. Such molecules are useful in therapy.
申请公布号
EP2877248(A1)
申请公布日期
2015.06.03
申请号
EP20130740316
申请日期
2013.07.26
申请人
OSPEDALE SAN RAFFAELE S.R.L.;UNIVERSITÀ DEGLI STUDI DI MILANO - BICOCCA
发明人
BIANCHI, MARCO EMILIO;CASALGRANDI, MAURA;VENEREAU, EMILIE JOELLE;BRUNELLI, SILVIA
