发明名称 滅菌済み輸液製剤の製造方法
摘要 <p><P>PROBLEM TO BE SOLVED: To provide a heating sterilization method for not generating highly viscous deposit without executing complicated preparation treatment of a stabilizer, in the case in which the highly viscous deposit is to be generated in a part of a container when cooling, to a room temperature after heating sterilization at high temperature, an infusion preparation including: a soft bag; a cylindrical discharge port attached to the soft bag; a communication blocking weak seal part formed so as to surround the discharge port; a liquid chemical chamber for fixing at the time of use, formed as a communication space of the space inside the soft bag closer to the discharge port side than the communication blocking weak seal part and the space inside the discharge port; and a liquid chemical for mixing at the time of use, which is housed in the liquid chemical chamber for mixing at the time of use and contains a non-ionic surfactant having a polyoxyethylene chain. <P>SOLUTION: The heating sterilization is performed by adjusting an installation angle of the infusion preparation so as to be such a state that 70% or more of the liquid chemical for mixing at the time of use is housed in the space inside the discharge port. <P>COPYRIGHT: (C)2013,JPO&INPIT</p>
申请公布号 JP5727272(B2) 申请公布日期 2015.06.03
申请号 JP20110068017 申请日期 2011.03.25
申请人 テルモ株式会社 发明人 安藤 裕美;伊藤 宏
分类号 A61J1/05;A61K9/08;A61K31/07;A61K31/122;A61K31/355;A61K31/59;A61K47/10;A61K47/34;A61P3/00 主分类号 A61J1/05
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