Oxidative homo-coupling reactions of aryl boronic acids using a porous copper metal-organic framework as a highly efficient heterogeneous catalyst

摘要

The disclosure provides methods for the use of open metal frameworks to catalyze coupling reactions.

主权项

1. A method to connect aryls by homocoupling comprising contacting a porous metal organic framework (MOF) or a porous metal organic polyhedral (MOP) with boronic acid substituted aryls wherein the MOF or MOP catalyze the synthesis of a biaryl through a homo-coupling reaction, wherein the MOF or MOP comprises a plurality of linking moieties that have a substructure selected from the group consisting of (C1-C20)alkyl, (C3C20)cycloalky, aryl, (C1-C20)alkylamine, arylamine, and heterocycle; and wherein the substructure has one or more covalently attached CO2H linking clusters that undergo condensation with a copper metal and wherein the MOF or the MOP comprise open copper centers that are mono-dispersed throughout the pores.