| 主权项 |
1. A compound according to the structure of Formula (I) comprising: wherein R1 is selected from the group consisting of: C1-6alkyl, C1-6alkylamino, C1-6alkoxy, C3-6cycloalkylC1-6alkyl, C3-6cycloalkylC1-6alkylamino, C3-6cycloalkylC1-6alkoxy, C1-6alkoxyC1-6alkyl, C1-6alkoxyC1-6alkylamino, C1-6alkoxyC1-6alkoxy; and optionally terminally substituted with a hydroxyl, amino, thio, hydrazino, hydrazido, azido, acetylenyl, carboxyl, or maleimido group; n is 0 or an integer from 1-6; Het is a four-, five-, or six-membered saturated heterocycle wherein X, Y is CH or N, and at least one of X and Y is a nitrogen atom; Q is O, NH, or covalent bond; Z is O, CH2, CF2 or covalent bond; W is O, S; m is 0 or an integer from 1-6; p is an integer from 1-2; q is 0 or the integer 1; A is wherein
R2 is H or straight, branched or unsaturated C4-C24 alkyl or acyl;R3 is straight, branched or unsaturated C4-C24 alkyl or acyl; or a pharmaceutically acceptable salt thereof. |
