| 发明名称 | Method for the treatment of neurodegenerative diseases | ||
| 摘要 | Disclosed are methods for treating neurodegenerative diseases such as Amyotrophic Lateral Sclerosis, Alzheimer's Disease Parkinson's Disease, Myasthenia Gravis, Multifocal Motor Neuropathy, Primary Lateral Sclerosis, Spinal Muscular Atrophy, Kennedy's Disease, and Spinocerebellar Ataxia. | ||
| 申请公布号 | US9044459(B2) | 申请公布日期 | 2015.06.02 |
| 申请号 | US201313858667 | 申请日期 | 2013.04.08 |
| 申请人 | ALS THERAPY DEVELOPMENT INSTITUTE | 发明人 | Perrin Steven;Lincecum John Monteith;Gill Alan;Vieira Fernando |
| 分类号 | A61K39/395;C07K16/28;A61K45/00;A61K45/06;A61K38/17;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | Honigman Miller Schwartz and Cohn LLP | 代理人 | Honigman Miller Schwartz and Cohn LLP ;Bott Cynthia M.;O'Brien Jonathan P. |
| 主权项 | 1. A method of treating a patient with Amyotrophic Lateral Sclerosis, comprising administering to the patient a therapeutically effective amount of a compound that blocks the interaction of CD40 and CD40L in combination with a compound that blocks the interaction between CD28 and CD86 or between CD28 and CD80, wherein the compound that blocks the interaction of CD40 and CD40L is an anti-CD40L antibody. | ||
| 地址 | Cambridge MA US | ||