发明名称 In vitro method for analyzing a comparison of an indicative numberic value to a predetermined threshold so as to assess a likelihood of risk or presence of organ failure
摘要 The present invention relates to a testing system for analyzing a risk of developing organ failure or presence of organ failure, said system comprising a disposable testing device arranged to receive a biological sample, which testing system is further arranged with means for measuring within said sample the total amount of at least a first biological marker in the form of an intracellular enzyme, and comprising means for analyzing the measured value of said intracellular enzyme, and based on the results thereof being arranged to communicate the risk of developing organ failure or presence of organ failure to an operator of said testing system. The present invention also relates to a method for analyzing a risk of developing organ failure, or analyzing presence of organ failure.
申请公布号 US9045792(B2) 申请公布日期 2015.06.02
申请号 US201113822472 申请日期 2011.09.14
申请人 Calmark Sweden AB 发明人 Karlsson Mathias;Hiort af Ornäs Sofia
分类号 C12Q1/32;A61B5/145;A61B5/15;A61B5/151;G01N33/573;A61B5/00;A61B5/1455;A61B5/157;G06F19/24 主分类号 C12Q1/32
代理机构 Alston & Bird LLP 代理人 Alston & Bird LLP
主权项 1. An in- vitro method for analyzing a risk of developing organ failure or presence of organ failure, said method comprising the steps of: a) providing a biological sample, b) measuring the total amount of lactate dehydrogenase (LDH) present in the biological sample, c) measuring the total amount of albumin present within the provided sample, d) calculating an indicative numeric value (Ii) based on a relationship between the results obtained from steps (b) and (c), wherein the indicative numeric value (Ii) is calculated based upon a formula where Ii=(LDHtot/albumintot), e) comparing the calculated indicative numeric value (Ii) to a predetermined threshold, and f) analyzing the result of the comparison made in e) so as to assess the risk of developing organ failure or presence of organ failure.
地址 Karlstad SE