发明名称 |
Biomarkers for non-hodgkin lymphomas and uses thereof |
摘要 |
The disclosure provides a method of identifying a subject as having B-cell non-Hodgkin lymphoma (NHL) such as testing a sample from a subject for a mutation in one or more biomarkers. Also described are methods for classifying or monitoring a subject having, or suspected of having, B-cell non-Hodgkin lymphoma comprising testing the sample for a mutation in one or more biomarkers. |
申请公布号 |
US9045801(B2) |
申请公布日期 |
2015.06.02 |
申请号 |
US201313945439 |
申请日期 |
2013.07.18 |
申请人 |
British Columbia Cancer Agency Branch |
发明人 |
Morin Ryan D.;Marra Marco A.;Gascoyne Randy D.;Connors Joseph M. |
分类号 |
C12Q1/68;C12N9/10;C07K16/40;G01N33/68;G01N33/574 |
主分类号 |
C12Q1/68 |
代理机构 |
Riverside Law LLP |
代理人 |
Riverside Law LLP |
主权项 |
1. A cDNA nucleic acid molecule encoding a peptide comprising the amino acid sequence set forth in SEQ ID NO: 1 having a mutation at position Y641 with respect to the amino acid sequence set forth in SEQ ID NO: 1, wherein the mutation at position Y641 is selected from Y641N, Y641H, Y641F, Y641S and Y641C. |
地址 |
Vancouver CA |