| 发明名称 | Bioavailability enhancement delivery composition | ||
| 摘要 | A composition for increasing the bioavailability of an active pharmaceutical ingredient (“API”) in humans and animals, comprising a first water soluble surfactant having a cloud point greater than about 37° C., a second water soluble surfactant having a cloud point greater than about 37° C., wherein a mixture of the first surfactant and the second surfactant comprises a cloud point less than about 37° C. | ||
| 申请公布号 | US9044394(B2) | 申请公布日期 | 2015.06.02 |
| 申请号 | US201113308331 | 申请日期 | 2011.11.30 |
| 申请人 | PruGen IP Holdings, Inc. | 发明人 | Patel Bhiku G. |
| 分类号 | A61K31/40;A61K31/16;A61K9/107;A61K47/22;A61K47/26;A61K9/48;A61K31/202;A61K31/00;A61K47/14;A61K47/44 | 主分类号 | A61K31/40 |
| 代理机构 | Quarles & Brady LLP | 代理人 | Regelman Dale F.;Quarles & Brady LLP |
| 主权项 | 1. A composition for increasing the bioavailability of an active pharmaceutical ingredient (“API”) in humans and animals, consisting of: polyoxyethylene sorbitan monooleate having a cloud point greater than about 37° C.; tocopheryl polyethylene glycol succinate having a cloud point greater than about 37° C.; an API selected from the group consisting of acetaminophen and atorvastatin; a terpene; wherein a mixture of said polyoxyethylene sorbitan monooleate, said tocopheryl polyethylene glycol succinate, comprises a cloud point less than about 37° C. | ||
| 地址 | Scottsdale AZ US | ||