Methods to control dissolved gas

摘要

A method of sensing nucleotide reactions includes flowing at least one nucleotide solution from a container of at least two containers of a sensor system. The sensor system includes a sensor sensitive to a byproduct of nucleotide incorporation. Each container of the at least two containers includes a different nucleotide solution. The sensor system enters an idle mode after flowing. The method further includes cycling the at least two containers through at least two cycles. Each cycle includes depressurizing the at least two containers for a first period and pressurizing the at least two containers for a second period. The method also includes pressurizing the at least two containers when the sensor system enters an active mode.

主权项

1. A method to reduce error in detecting nucleotide reactions, the method comprising:
flowing at least one nucleotide solution from one of at least two containers of a sensor system into an electronic sensor system including a sensor sensitive to detect a byproduct of nucleotide incorporation including pH changes, each container including a different nucleotide solution, the sensor system entering an idle mode after flowing; cycling the at least two containers through at least two cycles, each cycle including depressurizing the at least two containers for a first period and pressurizing the at least two containers for a second period; and pressurizing the at least two containers when the sensor system enters an active mode.