Electrode structures and methods for their use in cardiovascular reflex control

摘要

Devices, systems and methods are described by which the blood pressure, nervous system activity, and neurohormonal activity may be selectively and controllably reduced by activating baroreceptors. A baroreceptor activation device is positioned near a baroreceptor, preferably a baroreceptor located in the carotid sinus. A control system may be used to modulate the baroreceptor activation device. The control system may utilize an algorithm defining a stimulus regimen which promotes long term efficacy and reduces power requirements/consumption. The baroreceptor activation device may utilize electrodes to activate the baroreceptors. The electrodes may be adapted for connection to the carotid arteries at or near the carotid sinus, and may be designed to minimize extraneous tissue stimulation.

主权项

1. A method, comprising:
implanting a baroreceptor activation device within a patient, the baroreceptor activation device including an electrode, wherein the baroreceptor activation device is implanted such that the electrode is in contact with an outer surface of a blood vessel and proximate a baroreceptor in a wall of the blood vessel; and activating, deactivating, or otherwise modulating the baroreceptor activation device as part of a baroreflex therapy.