发明名称 |
Use of chromen-4-one derivatives |
摘要 |
The invention relates to the use of chromen-4-one derivatives of the formula I;where R1 and R2 may be identical or different and are selected from H, —C(═O)—R7, —C(═O)—OR7, alkyl groups, alkenyl groups, hydroxyalkyl groups and/or cycloalkyl groups and/or cycloalkenyl groups, R3 is H or alkyl groups, R4 is H or OR8, R5 and R6 are selected from —H, —OH, alkyl groups, alkenyl groups and hydroxyalkyl groups, and R7 is H, alkyl groups, a polyhydroxyl compound, such as, preferably, an ascorbic acid radical or glycosidic radicals, and R8 is H or alkyl groups, where at least two of the substituents R1, R2 and R4-R6 are different from H or at least one substituent from R1 and R2 is —C(═O)—R7 or —C(═O)—OR7, for the care, preservation or improvement of the general state of the skin or hair. |
申请公布号 |
US9044409(B2) |
申请公布日期 |
2015.06.02 |
申请号 |
US200711869192 |
申请日期 |
2007.10.09 |
申请人 |
Merck Patent GmbH |
发明人 |
Carola Christophe;Buchholz Herwig;Huber Sylvia;Rosskopf Ralf |
分类号 |
A61K31/05;A61K31/122;A61K31/35;A61K31/352;A61K8/49;A23L1/30;A61K45/06;A61Q5/00;A61Q17/04;A61Q19/00;A61Q19/08;A61Q11/00;A61Q19/02 |
主分类号 |
A61K31/05 |
代理机构 |
Millen, White, Zelano & Branigan, P.C. |
代理人 |
Millen, White, Zelano & Branigan, P.C. |
主权项 |
1. A method for reducing or suppressing skin unevenness, wrinkles, fine lines, rough skin or large-pored skin, comprising applying to the skin or hair of a human patient at least one compound of formula Ia or a salt thereof, with the proviso that said human is not suffering from pigment defects of the skin. |
地址 |
Darmstadt DE |