主权项 |
1. A method for making 5,5′-dialkyl-biphenyl-2,2′-diols, comprising the following steps:
(i) methylating biphenyl-2,2′-diol using dimethyl sulfate, to obtain 2,2′-dimethoxy-biphenyl; (ii) acylating the 2,2′-dimethoxy-biphenyl with an alkionyl chloride to obtain 2,2′-dimethoxy-5,5′-dialkionyl-biphenyl; (iii) reducing the 2,2′-dimethoxy-5,5′-dialkionyl-biphenyl to obtain 2,2′-dimethoxy-5,5′-dialkyl-biphenyl; (iv) demethylating the 2,2′-dimethoxy-5,5′-dialkyl-biphenyl by reaction with aluminium chloride and thiourea; and (v) recovering the 5,5′-dialkyl-biphenyl-2,2′-diol thus obtained. |