发明名称 X-ray contrast media compositions and methods of using the same to treat, reduce or delay the onset of CNS inflammation and inflammation associated conditions
摘要 Embodiments disclosed herein relate to improved X-ray contrast media compositions and methods of using the same for treating symptoms related to allergic reactions, inflammatory conditions, symptoms of the common cold and certain cancers.
申请公布号 US9044449(B2) 申请公布日期 2015.06.02
申请号 US201313889124 申请日期 2013.05.07
申请人 3E THERAPEUTICS CORPORATION 发明人 Lasser Elliott C.
分类号 A61K33/30;A61K31/196;A61K31/167;A61K31/7008;A61K45/06 主分类号 A61K33/30
代理机构 Pillsbury Winthrop Shaw Pittman LLP 代理人 Pillsbury Winthrop Shaw Pittman LLP
主权项 1. A method of treating inflammation of the central nervous system (CNS) in a human in need thereof , comprising administering to the human in need thereof a composition comprising one or more X-ray contrast media in an amount sufficient to treat said inflammation of the CNS and zinc in an amount sufficient to activate an angiotensin converting enzyme (ACE), wherein the amount of zinc is from 0.1×10−3 mg to 4×10−3 mg, and wherein a) the X-ray contrast media comprises a triiodinated, benzene moiety; b) the X-ray contrast media is a non-ionic monometer, non-ionic dimer, ionic monomer or ionic dimer; and c) the composition is administered directly to CNS tissue.
地址 La Jolla CA US