发明名称 |
Compounds and compositions for mitigating tissue damage and lethality |
摘要 |
Embodiments of the present invention provide compounds and compositions thereof, which are effective for mitigating tissue damage or lethality induced by an agent, and methods of making and using the same. |
申请公布号 |
US9045474(B2) |
申请公布日期 |
2015.06.02 |
申请号 |
US201113813923 |
申请日期 |
2011.08.03 |
申请人 |
The Regents of the University of California |
发明人 |
Schiestl Robert H.;Rivina Yelena O.;Jung Michael E.;Damoiseaux Robert |
分类号 |
C07D405/14;A61K31/4704;A61K31/4709;A61P39/02;C07D471/04;A61K31/00;A61K31/381;A61K31/437;G01N33/50;A61K45/06;A61N5/10;C07D333/38;C07D409/12;C12Q1/02 |
主分类号 |
C07D405/14 |
代理机构 |
Foley Hoag LLP |
代理人 |
Halstead David P.;Foley Hoag LLP |
主权项 |
1. A method of mitigating tissue damage, genetic instability, or lethality induced by radiation or a chemical carcinogen in a cell, the method comprising contacting the cell with a compound having a structure of Formula IAor a pharmaceutically acceptable salt thereof. |
地址 |
Oakland CA US |