SALT AND POLYMORPH OF PYRAZOLOPYRIMIDINONE COMPOUND AND DRUG COMPOSITION PREPARATION METHOD AND USE THEREOF

摘要

The present invention relates to salts and a pharmaceutically acceptable polymorph solvate hydrate dehydrate co crystal anhydride or amorphous form of a novel pyrazolopyrimidinone compound as shown in general formula (I) and to a pharmaceutical composition and a pharmaceutical unit dosage form comprising same wherein X represents an organic or inorganic acid preferably maleic acid succinic acid hydrochloric acid methylsulfonic acid and the like. The present invention further relates to a co crystal or a composite of the pyrazolopyrimidinone compound and a pharmaceutical composition comprising same. The present invention also relates to a preparation method of the abovementioned substances and the use thereof and pharmaceutical preparations comprising these salts and crystal forms.