| 摘要 |
<p>Provided are pro-drugs of D-gamma-glutamyl-[D/L] -tryptophan of Formula I wherein G is C1-8 alkyl or benzyl, T is C1-8 alkyl or benzyl, and * is a chiral carbon in a (R) or (S) configuration, provided that when * is in the (R) configuration, at least one of G and T is C-C alkyl. Further provided is the use of the pro-drugs in pharmaceutical compositions. D-gamma-glutamyl-D-tryptophan and D-gamma-glutamyl-L-tryptophan may be useful in the treatment of various diseases particularly those that are immune system related.</p> |
